DURECT Corporation (NASDAQ:DRRX)
Shares of DURECT Corporation (NASDAQ:DRRX) traded higher in the market after the company announced it had entered into a development and commercialization agreement with Novartis AG (ADR) (NYSE:NVS) division Sandoz AG. The agreement is for the development and marketing of non-opioid analgesic POSIMIR (R).
Under the terms of the agreement, DURECT Corporation (NASDAQ:DRRX) is to receive $20 million in up-front payments from the Novartis division. The company also stands to receive an additional $43 million in development and regulatory milestones. An additional $230 million on sales-based milestones is also at stake depending on how the drug turns out in trials.
DURECT Corporation (NASDAQ:DRRX) has been given the go-ahead to complete an ongoing PERSIST Phase 3 clinical trial for the novel treatment. It will also be responsible for any Foods and Drug Administration interactions leading to approval. The company could receive $43 million as soon as it makes an NDA application – possibly as early as Q1 2018. The deal should close in the second quarter of the year.
“We believe that POSIMIR has the potential to become a cornerstone of multi-modal post-operative pain management. As a non-opioid local analgesic, we believe POSIMIR may be an important contributor to the on-going efforts to reduce the use of opioid-based medications following surgery, “said Chief executive officer James E. Brown.
If approved, POSIMIR will fight for market share in a multi-billion pain relief industry that currently boasts of the likes of Pacira with its Exparel treatment. The drug generated about $300 million in revenues last year.
POSIMIR is a novel treatment designed to provide three days of continuous pain relief for patients who have undergone surgery. DURECT Corporation (NASDAQ:DRRX) is currently undertaking Phase 3 trials on patients who have undergone a laparoscopic cholecystectomy. Dosing of patients should be completed in the third quarter after which the company says it will release results.
The development and marketing agreement is a great deal for DURECT Corporation (NASDAQ:DRRX) given that Sandoz comes with a robust sales and marketing team that it can take advantage off. The Novartis division also comes into the deal with a range of state of the art technologies that should benefit Durect in the long run.
Sandoz’s deal should go a long way in validating DURECT Corporation (NASDAQ:DRRX)’s balance sheet given the amount of money the company is set to receive leading to the approval of POSIMIR. Sandoz partnership also goes a long way in validating the company’s technology as well as its clinical program.
I have no positions in any of the stocks mentioned, and have no plans to initiate any positions within the next 72 hours. All information, including any data, is provided without any guarantees of accuracy.
About the author: Monica Gray has an undergraduate degree in Accounting and an MBA – earned with Honors. She has six years of experience in the financial markets and has been a securities analyst for the past two years.