Aptose Biosciences Inc (NASDAQ:APTO)

New High for Aptose Biosciences Inc (NASDAQ:APTO)

Aptose Biosciences Inc (NASDAQ:APTO)

Aptose Biosciences Inc (NASDAQ:APTO) shares have hit a new 52-week high, are up over 17%, and trading around the $2 handle in mid-afternoon trading. Volume is heavy for the biotech’s shares as they are trading about seven times their daily average.

Aptose Biosciences Inc (NASDAQ:APTO)

Aptose Biosciences Inc (NASDAQ:APTO) is scheduled to be releasing their Q3 2017 earnings report tomorrow, November 14, 2017, after the close of trading. According to Zacks Investment Research, the consensus of analysts are expecting an EPS loss of (-$0.13) per share.

Canadian-based Aptose Biosciences Inc (NASDAQ:APTO) is a clinical-stage biotechnology company committed that develops personalized therapies designed to address unmet medical needs in cancer patients. Aptose is advancing new therapeutics focused on novel cellular targets on the leading edge of cancer treatment. The company’s pipeline of small molecule cancer therapeutics includes products designed to provide single agent efficacy and to enhance the efficacy of other anti-cancer therapies and regimens without overlapping toxicities.

APTO Stock Performance

Shareholders of Aptose Biosciences Inc (NASDAQ:APTO) have experienced a good year. Year-to-date, APTO stock is up over 22%, and for the year the gain is an even more impressive 65%. Analysts have given APTO stock a consensus, one-year price target of $3.15. The stock’s 52-week low was established last April at a price of $0.78. Today’s price action, should it hold, will establish a new 52-week high – besting the old mark of $1.79. Given the strong upward momentum of the stock, it is not surprising that the shares have a Relative Strength score of 77 – a level that most traders consider to be a sign of an “overbought” condition.

Aptose Biosciences Inc (NASDAQ:APTO) has no reported sales. Accordingly, their earnings have been negative since 2012. In the past three years, the per share losses have expanded. In 2014 the per share loss was (-$0.53), followed the next year by (-$0.97), and (-$1.15) for 2016.

I have no positions in any of the stocks mentioned, and have no plans to initiate any positions within the next 72 hours. All information, including any data, is provided without any guarantees of accuracy.

Don’t miss out! Stay informed on $APTO and receive breaking news on other hot stocks by signing up for our free newsletter!

About the author: Steve Clark is a 23-year Wall St professional with stints in M&A, risk management, and algorithm trading. Steve keeps his head in the game by looking for, and writing about, small companies that often get overlooked by the big investment firms.

OncoSec Medical Inc. (NASDAQ:ONCS)

OncoSec Medical Inc. (NASDAQ:ONCS) To Make Key Presentations

OncoSec Medical Inc. (NASDAQ:ONCS)

OncoSec Medical Inc. (NASDAQ:ONCS) shares gained 10.1% after the company said it will present updated clinical data on the study of ImmunoPulse IL-12, its lead oncology program. The biotechnology company will make the presentation at the upcoming 9th World Congress of Melanoma.

OncoSec Medical Inc. (NASDAQ:ONCS)

ImmunoPulse IL-12 Presentations

In addition, OncoSec Medical Inc. (NASDAQ:ONCS) is to present updated clinical data from its Phase 2 Investigator Sponsored trial in patients with unresectable metastatic melanoma. The presentation will occur at the upcoming Society for Immunotherapy of Cancer (“SITC”) 32nd Annual Meeting to be held on November 8-12, 2017,

ImmunoPulse IL-12 is a nonviral gene delivery platform designed to utilize the power of the human immune system to target and attack tumors in the body. It is currently in Phase 2 clinical monotherapy trial, for the treatment of stage three and four melanoma.

A presentation by Dr. Alain Algazi will contrast the candidate drug to its combination with pembrolizumab. The presentation will also include clinical and biomarker data from a recently completed Phase 3 monotherapy trial.

“These data, along with the emerging clinical data from the phase 2 combination study, further support the rationale for our global, open-label, registration-directed phase 2b clinical trial, PISCES/KEYNOTE-695, which we anticipate reporting initial data in mid-2018,” said CEO Punit Dhillon.

 ONCS Stock Performance

Investor confidence on OncoSec Medical Inc. (NASDAQ:ONCS) is slowly building following a string of positive news on the development of the company’s lead oncology program. The stock has bounced back from multi-year lows of below $1 a share and bullish momentum continues to grow in strength.

However, the stock is still down by more than 5% for the year after coming under pressure after rising to $1.50 share. OncoSec Medical Incorporated faces immediate resistance at $1.25 a close above which could see the stock making a push for the $1.50 mark.

OncoSec Medical Inc. (NASDAQ:ONCS) has elicited significant investor interest in the recent past as most of them take note of its robust and differentiated approach in developing cancer treatments. The company is currently merging over two decades of research and development processes to accelerate the development of its lead candidate product.

The company’s flagship product, ImmunoPulse IL-12 has already shown to deliver equal gene transmission rates while maintaining a high safety profile. OncoSec Medical Inc. (NASDAQ:ONCS) is advancing the treatment into Phase 2 trials with projected milestone for treatment approval set for 2019.

I have no positions in any of the stocks mentioned, and have no plans to initiate any positions within the next 72 hours. All information, including any data, is provided without any guarantees of accuracy.

Don’t miss out! Stay informed on $ONCS and receive breaking news on other hot stocks by signing up for our free newsletter!

About the author: Monica has an undergraduate degree in Accounting and an MBA she earned – with Honors. She has six years of experience in the financial markets and has been an analyst for the past two years.

Delcath Systems, Inc. (NASDAQ:DCTH)

Is Delcath Systems, Inc. (NASDAQ:DCTH) A Buy Or A Sell?

Is Delcath Systems, Inc. (NASDAQ:DCTH)

Yesterday, shares of Delcath Systems, Inc. (NASDAQ:DCTH) rallied by 27.8% to end the day at $0.18. Regulatory approvals and commercial progress in Europe for the company’s proprietary products continues to strengthen investor’s sentiments on the stock. Fueling demand for DCTH shares is talk that the company remains undervalued at current trading levels.

Delcath Systems, Inc. (NASDAQ:DCTH)
Candle graph of Decalth share pricing

Liver Cancer Treatment Focus

Delcath Systems, Inc. (NASDAQ:DCTH) is a medical device company with great interest in the treatment of various types of cancers. The company boasts of proprietary medical technologies that are currently being used to deliver high dose chemotherapy to the liver. Its lead product is Melphalan Hydrochloride used in combination with the Delcath Hepatic Delivery System.

Delcath Systems, Inc. (NASDAQ:DCTH) technology targets a wide variety of cancers that affect the liver. Nearly 700,000 people are diagnosed with liver cancer every year presenting a target market worth about $700 million in revenues.

Chemosat Treatment Factor

Delcath Systems, Inc. (NASDAQ:DCTH) has had its share of challenges on the clinical trial front as its percutaneous hepatic perfusion system failed to meet FDA threshold for approval. However, things are starting to look up after the company posted positive results for patients who received CHEMOSAT treatment for metastatic melanoma.

Impressive sales of the CHEMOSAT delivery system continues to affirm talk why Delcath Systems remains an exciting pick at current trading levels. Expansion in Europe has allowed the company to complete over 250 treatments on the road to validating its effectiveness.

Immediate Risks

In addition, the company is also in the process of determining the safety and efficacy of its proprietary technology in a number of ongoing clinical trials. One of the trials is targeting Ocular Melanoma as well as Hepatocellular carcinoma. The release of FOCUS Phase 3 interim safety analysis could have a significant impact on the stock price.

A major concern with Delcath Systems, Inc. (NASDAQ:DCTH) stock is the fact that it has lost a significant amount of value over the past few years. The NASDAQ Capital Market is poised to rule on its exchange listing on August 14, 2017 as the stock price has gone below the $1 a share minimum bid requirement.

The management could seek a 180-day extension to allow it sort out the mess. The company may pursue a reverse stock split to shore up the share price.

I have no positions in any of the stocks mentioned, and have no plans to initiate any positions within the next 72 hours. All information, including any data, is provided without any guarantees of accuracy.

Don’t miss out! Stay informed on $DCTH and receive breaking news on other hot stocks by signing up for our free newsletter!

About the author: Steve Clark is a 23-year Wall St professional with stints in M&A, risk management, and algorithm trading. Steve keeps his head in the game by looking for, and writing about, small companies that often get overlooked by the big investment firms.

NewLink Genetics Corporation (NASDAQ:NLNK) Has a Big Day

NewLink Genetics Corporation (NASDAQ:NLNK)

NewLink Genetics Corporation (NASDAQ:NLNK) gained 17.5% today on over five times the average daily volume. NewLink Genetics announced that it will be presenting at the 2017 American Association of Cancer Research annual meeting. Experts claim that when a firm agrees to participate in such an event, there is a high likelihood that they will be presenting positive news on one of their drug or treatment candidates.

NewLink Genetics (NASDAQ:NLNK) is a biopharmaceutical company at the forefront of discovering, developing and commercializing novel immuno-oncology product candidates to improve the lives of cancer patients. NewLink Genetics’ product candidates are designed to harness multiple components of the immune system to combat cancer.

Tuesday, February 28, 2017, NewLink Genetics Corp. (NASDAQ:NLNK) reported Q4 and full year earnings. NewLinks lost $13.5 million in its fourth quarter. The Ames, IA-based company said it had a loss of $0.46/share. The results exceeded Wall Street expectations. The average of analysts estimates of four analysts was reported to be a loss of $0.66/share. NewLink Genetics posted revenue of $12.7 million in the period – beating analyst estimates of $4.3 million. NewLink posted a yearly loss of $85.2 million, or $2.94 per share. Revenue was reported as $35.8 million.

NewLink Genetics Corp. (NASDAQ:NLNK) shares have risen 38.2% this week and 92% YTD. NLNK shares started the year around $10 and have risen in value each month for the past three months but are still over 4% from their 52-week highs. Of the six firms that follow NewLink Genetics Corp. (NASDAQ:NLNK), four rate the shares as a “Strong Buy” and two rate NLNK shares as a “Hold”.

3/2/2017
Ticker Symbol NLNK
Last Price a/o 5:08 PM EST  $                    19.73
Average Volume                    281,750
Market Cap (mlns)  $                  578.88
Sales (mlns) $30.70
Shares Outstanding (mlns) 29.34
Share Float (mlns) 21.62
Shortable Yes
Optionable Yes
Inside Ownership 1.50%
Short Float 10.61%
Short Interest Ratio 8.14
Quarterly Return 72.16%
YTD Return 91.93%
Year Return -0.85%

I have no positions in any stocks mentioned, and no plans to initiate any positions within the next 96 hours. All information, or data, is provided with no guarantees of accuracy. 

About the author: Steve Clark is a 23-year Wall St professional with stints in M&A, risk management, and algorithm trading.

Agenus Inc. (NASDAQ:AGEN) Deal With Incyte Corp. (INCY) Looks Good

Agenus Inc. (NASDAQ:AGEN)

Shares of small-cap Agenus Inc. (NASDAQ:AGEN) are up, on heavy volumes, on news that Incyte Corporation (NASDAQ:INCY) has essentially substituted a development and commercialization agreement into what essentially amounts to a “Call” option on future revenues of Agenus’ drugs GITR and OX40. The new agreement gives all future development and commercialization responsibilities to Incyte. Agenus receives a $28 million up-front payment and royalty payments on 15% of global net sales. AGEN shares are up over 10%. The ongoing TIM-3 and LAG-3 antibody programs remain royalty-bearing programs, at tiered rates of 6 to 12 percent, with Incyte retaining exclusive world-wide clinical development and commercial responsibilities. Also released this morning was news that Incyte would buy 10 million shares of AGEN at $6/share.

Lexington, MA-based Agenus Inc. (NASDAQ:AGEN) discovers and develops cancer treatments that engage the body’s immune system. Incyte Corporation (NASDAQ:INCY), based in Wilmington, DE, is a $23 billion company discovers, develops, and commercializes proprietary therapeutics in oncology in the United States and internationally.

Agenus Inc. (NASDAQ:AGEN) has an impressive amount of product in their pipeline. Five drugs are in pre-clinical data gathering. Four are in Phase 1 clinical trials, one is in its Phase 2 clinical trial, and two are completing their Phase 3 trials.

In 2014 Agenus Inc. (NASDAQ:AGEN) reported sales of just $7 million but in 2015 that figure improved to $24.8 million. However AGEN shareholders have experienced EPS losses for the past five years – $1.21, $$0.51, $1.12, $0.71, and $1.13 in 2015. Four analysts cover AGEN and three rate the shares as a “Strong Buy” while one rates AGEN shares as a “Hold”.

I have no positions in any stocks mentioned, and no plans to initiate any positions within the next 96 hours. All information, or data, is provided with no guarantees of accuracy.

2/14/2017
Ticker Symbol AGEN
Last Price a/o 10:47 AM EST  $                      4.62
Average Volume                1,030,000
Market Cap (mlns)  $                  354.07
Sales (mlns) $24.60
Shares Outstanding (mlns) 85.94
Share Float (mlns) 81.86
Shortable Yes
Optionable Yes
Inside Ownership 1.60%
Short Float 15.21%
Short Interest Ratio 12.08
Quarterly Return -20.16%
YTD Return 0.00%
Year Return 45.58%
Merrimack Pharmaceuticals Inc (NASDAQ:MACK)

Actinium Pharmaceuticals (NYSE: ATNM) Jumps Over 30% on Massive Volumes

Actinium Pharmaceuticals Inc. – NYSE: ATNM

Actinium Pharmaceuticals gained over 30% in today’s trading on exceptionally heavy volumes. ATNM, traded on the NYSE, has an average daily volume of 275k, but today over 5.5 million shares traded hands.

New York, NY-based Actinium Pharmaceuticals is a biotech company that develops innovative targeted payload immunotherapies for the treatment of advanced cancers. The Company’s radioimmunotherapy product candidates are based on the combination of the cancer targeting precision of monoclonal antibodies (mAb) that seek out specific types of cells combined with the cytotoxic killing power of radioisotopes that unleash their energy once they have reached their target.

Actinium’s lead product is Iomab-B and is in its crucial Phase 3 clinical trial. Iomab-B is a myeloablative therapy, designed to destroy a patient’s bone marrow so that a patient can receive bone marrow from a donor via a transplant. Also in Actiniumn’s pipeline is its Alpha Particle Immunotherapy (APIT) platform. Being 100 times more powerful than beta particles, alpha therapy is effective in cancers that are not sensitive to beta irradiation such as victims of Acute Myeloid Leukemia (AML). AML treatment utilizing APIT has demonstrated extremely high cancer cell kill levels.

On January 27 – 28, 2017, in Dallas, TX, Chief Medical Officer, Dr. Mark Berger will present at the 3rd Annual Think Tank on Integrating New Molecular Targets in Acute Leukemias and Myeloproliferative Neoplasms. Dava Oncology is sponsoring the event as part of their Oncology Meeting Innovations program. Dr. Berger’s talk will focus on Actinium’s Iomab-B.

ATNM shares took a 20% dive in September when the company announced a public offering of an additional 8 million shares at $1.25 a piece plus offering the underwriters a 30-day option on an additional 15% of the sold stock. The price gapped down to below $1.40 and broke the $1 barrier in late October. Shares rebounded slightly and traded around the $1 handle until today when the stock took off and closed at $1.36 – just two cents short of the daily high.

Actinium Pharmaceuticals has yet to post any sales but institutions own over 10% of its shares – a fact which comforts some investors. ATNM had its largest earnings loss in 2012 when the company announced a loss of $7.58 per share. Earnings have never been positive; the last three years have seen per share losses under $1 with 2015 posting a loss of $0.55. Two firms follow Actinium Pharmaceuticals and both rate ATNM shares as a “Strong Buy”.

I have no positions in any stocks mentioned, and no plans to initiate any positions within the next 96 hours. All information, or data, is provided with no guarantees of accuracy.

2/3/2017
Ticker Symbol ATNM
Last Price a/o 3:59 PM EST  $                      1.36
Average Volume                    274,270
Market Cap (mlns)  $                    57.42
Sales (mlns)
Shares Outstanding (mlns) 55.75
Share Float (mlns) 51.06
Shortable Yes
Optionable Yes
Inside Ownership 8.50%
Short Float 2.31%
Short Interest Ratio 4.3
Quarterly Return 4.99%
YTD Return 17.17%
Year Return -50.00%